THE ROLE OF SELENIUM TOWARDS DEVELOPMENT IN CHILDREN OF AUTIS SPECTRUM DISORDER (ASD)

Neny  Triana; Mohammad  Sulkhan; Mexitalia Setiawati  Estiningtyas

Neny Triana STIKES Karya Husada Kediri
Mohammad Sulkhan STIKES Karya Husada Kediri
Mexitalia Setiawati Estiningtyas STIKES Karya Husada Kediri

Keywords: Selenium, Development, Autism Spectrum Disorder

Abstract

Autism Spectrum Disorder (ASD) is a developmental disorder, which is
characterized by two symptoms, barriers to communication / social interaction and
restrictive (limited) / repetitive (repetitive) behavior. Development is closely related to
the nervous system, especially the cerebrum. abnormalities in ASD children are related to
the right and left hemispheres, and each hemisphere is divided into four lobes according
to their function, the frontal lobes regulate behavior, language and memory. Temporal
lobe to control hearing, language understanding. The parietal lobe to interpret taste (pain,
temperature and touch) and the occipital lobe to interpret visual stimulation. Handling of
ASD is one of them with Complementary and Alternative Medicine (CAM) biological
therapy, namely selenium supplements. Selenium as an improvement in specific, nonspecific,
and antioxidant immune responses. Selenium as an element selenoprotein as an
essential component of the enzyme glutathione peroxidase (GPx). GPx acts to reduce
hydrogen peroxide (Hâ‚‚Oâ‚‚) to water (H2O), improve neuronal degeneration. Selenium
as an antioxidant compound, is an electron-giving compound (donor electron) and
counteracts the negative effects of oxidants.